Low hygroscopic aripiprazole drug substance and processes for the preparation thereof
The present invention provides an improved low hygroscopic form, form E, of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their original solubility even when a medicinal preparation containing the aripiprazole anhydride crystals is stored for an e...
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| creator | Abe, Kaoru Aoki, Satoshi Kawasaki, Junichi Nishioka, Yoshihiro Yabuuchi, Tsuyoshi Kobayashi, Noriyuki Oi, Yoshihiro Fujimura, Tsutomu Ishigami, Makoto Tominaga, Michiaki Utsumi, Naoto Taniguchi, Youichi Yamada, Shohei Shinhama, Koichi Fujimoto, Kiyoshi Tomikawa, Kenji Takahashi, Masanori Bando, Takuji Nakagawa, Tomonori |
| description | The present invention provides an improved low hygroscopic form, form E, of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their original solubility even when a medicinal preparation containing the aripiprazole anhydride crystals is stored for an extended period. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SEPARATION SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TRANSPORTING |
| title | Low hygroscopic aripiprazole drug substance and processes for the preparation thereof |
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