SUSTAINED RELEASE MICROPELLETS AND PROCESS FOR PRODUCING THE SAME

SUSTAINED RELEASE MICROPELLETS AND PROCESS FOR PRODUCING THE SAME

Sustained release micropellets showing a stable controlled-release of a drug without being affected by the changes in pH value etc., characterized by being produced by coating core particles with a layer containing a water-soluble drug and further forming a film layer containing a water-insoluble po...

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Bibliographische Detailangaben
Hauptverfasser: HOSONO, TETSUYA, KITANO, EISAKU, HAMANO, FUMIYA, YONEDA, FUMIO
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:Sustained release micropellets showing a stable controlled-release of a drug without being affected by the changes in pH value etc., characterized by being produced by coating core particles with a layer containing a water-soluble drug and further forming a film layer containing a water-insoluble polymer compound and a plasticizer on the thus obtained particles, locating a water-soluble filler layer between the water soluble drug-containing layer and the film layer, and having an average particle size of 300 mu m or less; medicinal compositions containing these micropellets; and a process for producing the same.