6-PHENYLDIHYDROPYRROLOPYRIMIDINEDIONE DERIVATIVES

6-PHENYLDIHYDROPYRROLOPYRIMIDINEDIONE DERIVATIVES

6-phenylpyrrolopyrimidinedione derivatives of the formula (I), and pharmaceutically acceptable salts thereof, wherein R , R , R , R and R are organic residues, L1 is a spacer group and R is C(O) NR R , -S(O)2NR R , ?-ON=CR R , or a heterocyclyl, aryl? or heteroaryl group, where R , R , R and R are o...

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Hauptverfasser: VIDAL JUAN, BERNAT, LOZA GARCIA, MARIA ISABEL, ESTEVE TRIAS, CRISTINA, FERNANDEZ GONZALEZ, FRANCO, RAVINA RUBIRA, ENRIQUE, SEGARRA MATAMOROS, VICTOR, SANZ CARRERAS, FERRAN
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:6-phenylpyrrolopyrimidinedione derivatives of the formula (I), and pharmaceutically acceptable salts thereof, wherein R , R , R , R and R are organic residues, L1 is a spacer group and R is C(O) NR R , -S(O)2NR R , ?-ON=CR R , or a heterocyclyl, aryl? or heteroaryl group, where R , R , R and R are organic residues, have therapeutic potential as A2 adenosine receptor inhibitors.