PHARMACEUTICAL COMPOSITION FOR PROPHYLAXIS AND TREATMENT OF CALCIUM METABOLISM DISORDERS COMPRISING CLODRONATE IN COMBINATION WITH GLYCERYL PALMITOSTEARATE

PHARMACEUTICAL COMPOSITION FOR PROPHYLAXIS AND TREATMENT OF CALCIUM METABOLISM DISORDERS COMPRISING CLODRONATE IN COMBINATION WITH GLYCERYL PALMITOSTEARATE

The object of the present invention is a pharmaceutical composition for oral use, in the form of hard gelatin capsules, which contains an excipient from the triglyceride class, for example atomized glyceryl palmitostearate, with double role, of lubricant and binder. The composition is used for the t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: DINU, TINCUTA, STANCU, CORNELIA, BADEA, IRINEL, LAZAR, LELIA-GEORGETA, DRAGHICI, VERONICA, ROTARU, MARIA
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator DINU, TINCUTA
STANCU, CORNELIA
BADEA, IRINEL
LAZAR, LELIA-GEORGETA
DRAGHICI, VERONICA
ROTARU, MARIA
description The object of the present invention is a pharmaceutical composition for oral use, in the form of hard gelatin capsules, which contains an excipient from the triglyceride class, for example atomized glyceryl palmitostearate, with double role, of lubricant and binder. The composition is used for the treatment and prophylaxis of calcium metabolism disorders, such as bone resorbtion, hypercalcemia and osteoporosis and contains as active ingredient a derivate of bisphosphonic acid, for example disodium clodronate. The active ingredient disodium clodronate tetrahydrate, granulated by fluidized bed method, is released from the preparation in a proportion of at least 75 % during the first 5 minutes and at least 95 % in 30 minutes.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP1408934A2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP1408934A2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP1408934A23</originalsourceid><addsrcrecordid>eNqNjcFOw0AMRHPpAQH_4B9AAtIDHJ2Nk1jaXa-8jtqcqgotJ0QjpX_TnyVF_YCeRqN5M_NQXdKAGtDRaOzQg5OQJLOxROhEIamkYfK45wwYWzAltEDRQDpYC47HAIEMG_GcA7ScRVvS_L-knDn24Ly0KhGNgOM1aHg114sd2wC9nxzp5CGhD2ySjVBX-KnafB9_lvJ808cKOjI3vJT5dCjLfPwqv-V8oPS2ff34rLf4Xt-B_AFMDERD</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PHARMACEUTICAL COMPOSITION FOR PROPHYLAXIS AND TREATMENT OF CALCIUM METABOLISM DISORDERS COMPRISING CLODRONATE IN COMBINATION WITH GLYCERYL PALMITOSTEARATE</title><source>esp@cenet</source><creator>DINU, TINCUTA ; STANCU, CORNELIA ; BADEA, IRINEL ; LAZAR, LELIA-GEORGETA ; DRAGHICI, VERONICA ; ROTARU, MARIA</creator><creatorcontrib>DINU, TINCUTA ; STANCU, CORNELIA ; BADEA, IRINEL ; LAZAR, LELIA-GEORGETA ; DRAGHICI, VERONICA ; ROTARU, MARIA</creatorcontrib><description>The object of the present invention is a pharmaceutical composition for oral use, in the form of hard gelatin capsules, which contains an excipient from the triglyceride class, for example atomized glyceryl palmitostearate, with double role, of lubricant and binder. The composition is used for the treatment and prophylaxis of calcium metabolism disorders, such as bone resorbtion, hypercalcemia and osteoporosis and contains as active ingredient a derivate of bisphosphonic acid, for example disodium clodronate. The active ingredient disodium clodronate tetrahydrate, granulated by fluidized bed method, is released from the preparation in a proportion of at least 75 % during the first 5 minutes and at least 95 % in 30 minutes.</description><edition>7</edition><language>eng ; fre ; ger</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2004</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20040421&amp;DB=EPODOC&amp;CC=EP&amp;NR=1408934A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20040421&amp;DB=EPODOC&amp;CC=EP&amp;NR=1408934A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DINU, TINCUTA</creatorcontrib><creatorcontrib>STANCU, CORNELIA</creatorcontrib><creatorcontrib>BADEA, IRINEL</creatorcontrib><creatorcontrib>LAZAR, LELIA-GEORGETA</creatorcontrib><creatorcontrib>DRAGHICI, VERONICA</creatorcontrib><creatorcontrib>ROTARU, MARIA</creatorcontrib><title>PHARMACEUTICAL COMPOSITION FOR PROPHYLAXIS AND TREATMENT OF CALCIUM METABOLISM DISORDERS COMPRISING CLODRONATE IN COMBINATION WITH GLYCERYL PALMITOSTEARATE</title><description>The object of the present invention is a pharmaceutical composition for oral use, in the form of hard gelatin capsules, which contains an excipient from the triglyceride class, for example atomized glyceryl palmitostearate, with double role, of lubricant and binder. The composition is used for the treatment and prophylaxis of calcium metabolism disorders, such as bone resorbtion, hypercalcemia and osteoporosis and contains as active ingredient a derivate of bisphosphonic acid, for example disodium clodronate. The active ingredient disodium clodronate tetrahydrate, granulated by fluidized bed method, is released from the preparation in a proportion of at least 75 % during the first 5 minutes and at least 95 % in 30 minutes.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2004</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjcFOw0AMRHPpAQH_4B9AAtIDHJ2Nk1jaXa-8jtqcqgotJ0QjpX_TnyVF_YCeRqN5M_NQXdKAGtDRaOzQg5OQJLOxROhEIamkYfK45wwYWzAltEDRQDpYC47HAIEMG_GcA7ScRVvS_L-knDn24Ly0KhGNgOM1aHg114sd2wC9nxzp5CGhD2ySjVBX-KnafB9_lvJ808cKOjI3vJT5dCjLfPwqv-V8oPS2ff34rLf4Xt-B_AFMDERD</recordid><startdate>20040421</startdate><enddate>20040421</enddate><creator>DINU, TINCUTA</creator><creator>STANCU, CORNELIA</creator><creator>BADEA, IRINEL</creator><creator>LAZAR, LELIA-GEORGETA</creator><creator>DRAGHICI, VERONICA</creator><creator>ROTARU, MARIA</creator><scope>EVB</scope></search><sort><creationdate>20040421</creationdate><title>PHARMACEUTICAL COMPOSITION FOR PROPHYLAXIS AND TREATMENT OF CALCIUM METABOLISM DISORDERS COMPRISING CLODRONATE IN COMBINATION WITH GLYCERYL PALMITOSTEARATE</title><author>DINU, TINCUTA ; STANCU, CORNELIA ; BADEA, IRINEL ; LAZAR, LELIA-GEORGETA ; DRAGHICI, VERONICA ; ROTARU, MARIA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP1408934A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2004</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>DINU, TINCUTA</creatorcontrib><creatorcontrib>STANCU, CORNELIA</creatorcontrib><creatorcontrib>BADEA, IRINEL</creatorcontrib><creatorcontrib>LAZAR, LELIA-GEORGETA</creatorcontrib><creatorcontrib>DRAGHICI, VERONICA</creatorcontrib><creatorcontrib>ROTARU, MARIA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DINU, TINCUTA</au><au>STANCU, CORNELIA</au><au>BADEA, IRINEL</au><au>LAZAR, LELIA-GEORGETA</au><au>DRAGHICI, VERONICA</au><au>ROTARU, MARIA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PHARMACEUTICAL COMPOSITION FOR PROPHYLAXIS AND TREATMENT OF CALCIUM METABOLISM DISORDERS COMPRISING CLODRONATE IN COMBINATION WITH GLYCERYL PALMITOSTEARATE</title><date>2004-04-21</date><risdate>2004</risdate><abstract>The object of the present invention is a pharmaceutical composition for oral use, in the form of hard gelatin capsules, which contains an excipient from the triglyceride class, for example atomized glyceryl palmitostearate, with double role, of lubricant and binder. The composition is used for the treatment and prophylaxis of calcium metabolism disorders, such as bone resorbtion, hypercalcemia and osteoporosis and contains as active ingredient a derivate of bisphosphonic acid, for example disodium clodronate. The active ingredient disodium clodronate tetrahydrate, granulated by fluidized bed method, is released from the preparation in a proportion of at least 75 % during the first 5 minutes and at least 95 % in 30 minutes.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; fre ; ger
recordid cdi_epo_espacenet_EP1408934A2
source esp@cenet
subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PHARMACEUTICAL COMPOSITION FOR PROPHYLAXIS AND TREATMENT OF CALCIUM METABOLISM DISORDERS COMPRISING CLODRONATE IN COMBINATION WITH GLYCERYL PALMITOSTEARATE
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T02%3A39%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=DINU,%20TINCUTA&rft.date=2004-04-21&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP1408934A2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true