METHODS AND NUCLEIC ACIDS FOR THE ANALYSIS OF HEMATOPOIETIC CELL PROLIFERATIVE DISORDERS

The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for ascertaining genetic and/or epigenetic parameters of genes for use in the differentiation, diagnosis, trea...

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Bibliographische Detailangaben
Hauptverfasser: NIMMRICH, INKO, BECKER, EVELYNE, MAIER, SABINE, MODEL, FABIAN, LESCHE, RALF, ADJORAN, PETER
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for ascertaining genetic and/or epigenetic parameters of genes for use in the differentiation, diagnosis, treatment and/or monitoring of hematopoietic cell proliferative disorders, or the predisposition to hematopoietic cell proliferative disorders.