E. coli strain for production L-leucine

There is provided a method for producing L-leucine using bacterium belonging to the genus Escherichia, which produces L-valine, L-isoleucine and L-homoleucine in an amount of less than 1% of that of L-leucine produced due to inactivation of ilvE gene coding for branched chain amino acid transaminase...

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Hauptverfasser: LUNTS, MARIA GRIGORIEVNA, KHOURGES, EVGENIY MOISEEVICH, ROSTOVA, YULIA GEORGIEVNA, VOROSHILOVA, ELVIRA BORISOVNA, IVANOVSKAYA, LIRINA VALERIEVNA, CUSYATINER, MIKHAIL MARKOVICH
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:There is provided a method for producing L-leucine using bacterium belonging to the genus Escherichia, which produces L-valine, L-isoleucine and L-homoleucine in an amount of less than 1% of that of L-leucine produced due to inactivation of ilvE gene coding for branched chain amino acid transaminase and produces increased amount of L-leucine due to increasing the activity of the aromatic amino acid transaminase encoded by tyrB gene.