VIRAL REPORTER PARTICLES

The present invention features a chimeric protein containing a beta-lactamase region and either a Vpr region or a Vpx region. The chimeric protein can be packaged into a viral reporter particle, introduced into a cell recognized by the viral particle and provide intracellular beta-lactamase activity...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MILLER, MICHAEL, D, SIMON, ADAM, J, HAZUDA, DARIA, J, LINEBERGER, JANET, E
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention features a chimeric protein containing a beta-lactamase region and either a Vpr region or a Vpx region. The chimeric protein can be packaged into a viral reporter particle, introduced into a cell recognized by the viral particle and provide intracellular beta-lactamase activity.