AQUEOUS SUSPENSION EYEDROPS AND PROCESS FOR PRODUCING THE SAME

An ophthalmic aqueous suspension preparation to serve as a cure for corneal herpes infection contains 9-Ä(2-hydroxyethoxy)methylÜguanine as an active ingredient and exhibits an improved stability. Specifically, the ophthalmic aqueous suspension preparation contains 0.2 to 5% by weight of 9-Ä(2-hydro...

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Bibliographische Detailangaben
Hauptverfasser:	OKAMOTO, TOMOYUKI, KASAMA, TOSHIO, SAITOH, KOUICHI, TOKUYAMA, SATORU, HANAZOME, ISAO, KISHIMOTO, YOKO, OGURO, SUSUMU
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TRAPPING
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Beschreibung
Zusammenfassung:	An ophthalmic aqueous suspension preparation to serve as a cure for corneal herpes infection contains 9-Ä(2-hydroxyethoxy)methylÜguanine as an active ingredient and exhibits an improved stability. Specifically, the ophthalmic aqueous suspension preparation contains 0.2 to 5% by weight of 9-Ä(2-hydroxyethoxy)methylÜguanine or a pharmaceutically acceptable salt thereof, 0.05 to 1% by weight of a partially saponified product of polyvinyl acetate, and 0.01 to 1% by weight of a nonionic surfactant and has a pH of 6 to 8. Preferably, the fine crystals have a short axis of 50 mu m or less and a long axis of 70 mu m or less in length and have a ratio of the long axis to the short axis of 10:1 or less.