MACROLIDE ANTIBIOTICS

The present invention relates to 11,12 gamma lactone ketolides of formula (I) wherein R, R1, R2, R3 are as defined herein and pharmaceutically acceptable salts and solvates thereof, to process for their preparation and their use in therapy or prophylaxis of systemic or topical bacterial infections i...

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Bibliographische Detailangaben
Hauptverfasser: MERLO, GIANCARLO, PAIO, ALFREDO, TIBASCO, JESSICA, ANDREOTTI, DANIELE, MARCHIORO, CARLA, BIONDI, STEFANO, MINGARDI, ANNA, SERI, CATIA, DAMIANI, FREDERICA, POZZAN, ALFONSO, ARISTA, LUCA, PIGA, ELISABETTA, NICCOLAI, DANIELA, TARSI, LUCA, CIRACO, MANUELA, LOCIURO, SERGIO, CARDULLO, FRANCESCA, TERRENI, SILVIA
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to 11,12 gamma lactone ketolides of formula (I) wherein R, R1, R2, R3 are as defined herein and pharmaceutically acceptable salts and solvates thereof, to process for their preparation and their use in therapy or prophylaxis of systemic or topical bacterial infections in a human or animal body.