PROCESS FOR PREPARATION OF CYANOPHENYLBENZOIC ACID DERIVATIVES
A process for the production of a compound represented by the following Formula (IV) or a salt thereof, comprising the steps of condensing with dehydration a compound represent by the following Formula (I) and 4-(aminomethyl)piperidine to obtain a compound represented by the following Formula (II);...
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Format: | Patent |
Sprache: | eng ; fre ; ger |
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Zusammenfassung: | A process for the production of a compound represented by the following Formula (IV) or a salt thereof, comprising the steps of condensing with dehydration a compound represent by the following Formula (I) and 4-(aminomethyl)piperidine to obtain a compound represented by the following Formula (II); protecting the secondary amine of the piperidine moiety to give a compound represented by the following Formula (III); and then reducing the imine moiety (in the Formulas, the wavy line may be, relative to the double bond, any of an E form, a Z form, or a mixture thereof, R represents a hydrogen atom, a C1-8 alkyl group etc., and R' represents a C1-8 alkylcarbonyl group, an arylcarbonyl group etc.). |
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