Production and use of an improved terminal deoxynucleotidyl transferase

Truncated terminal deoxynucleotidyl transferase (TdT) derivative (A) that is shorter than the wild type by up to 161 amino acids deleted from the N-terminus and which has 20-30 higher enzyme activity in solution containing cobalt (II) ions, is new. An Independent claim is also included for a method...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: SUPPMANN, BERNHARD, SCHMIDT, MANFRED, SOBEK, HARALD, SCHNEIDINGER, BERND, MUELLER, RAINER, SONN, KIRSTEN, PAJATSCH, MARKUS, CURDT, INGO
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Truncated terminal deoxynucleotidyl transferase (TdT) derivative (A) that is shorter than the wild type by up to 161 amino acids deleted from the N-terminus and which has 20-30 higher enzyme activity in solution containing cobalt (II) ions, is new. An Independent claim is also included for a method for recombinant production of (A) from calf thymus.