Method of controlling proliferation and differentiation of stem and progenitor cells

An expanded stem cell population expanded ex-vivo in a culture medium containing at least one copper chelator in an amount for permitting stem cells of said cell population to proliferate and, at the same time, for reducing a capacity of said stem cells to differentiate, said stem cells are hence ex...

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Bibliographische Detailangaben
Hauptverfasser: TREVES, AVI, PELED, TONY, FIBACH, EITAN
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:An expanded stem cell population expanded ex-vivo in a culture medium containing at least one copper chelator in an amount for permitting stem cells of said cell population to proliferate and, at the same time, for reducing a capacity of said stem cells to differentiate, said stem cells are hence expanded yet not further differentiated as compared to ex-vivo seeded stem cells from which said cell population developed.