(7-(3-CARBOXYPHENYL)-4-CHLOROISOQUINOLIN-1-YL)GUANIDINE

The invention described herein relates to a process for the preparation of (7-(3-carboxyphenyl)-4-chloroisoquinolin-1-yl)guanidine (I), intermediates thereto and new forms and formulations thereof, including the zwitterion monohydrate of (I), suitable for pharmaceutical use.

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Bibliographische Detailangaben
Hauptverfasser: MACRAE, JULIE ANN, BRUCKNER, ANNE, FITZGERALD, MICHAEL PAUL, NEWBURY, TREVOR JACK, STOREY, RICHARD ANTHONY, FISH, PAUL VINCENT, BUTTERS, MICHAEL
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The invention described herein relates to a process for the preparation of (7-(3-carboxyphenyl)-4-chloroisoquinolin-1-yl)guanidine (I), intermediates thereto and new forms and formulations thereof, including the zwitterion monohydrate of (I), suitable for pharmaceutical use.