IMMUNOGENIC COMPOSITION OF HEPATITIS C AND METHODS OF USE THEREOF

The present invention provides truncated HCV E2 polypepides. The invention HCV E2 polypeptides lack the HVR1 region that provides immune protection against HCV. The present invention also provides immunogenic compositions of such polypeptides and the methods of use thereof.

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Bibliographische Detailangaben
Hauptverfasser: NAKANO, EILEEN, T, HUMPHREYS, TOM, CLEMENTS, DAVID, E
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention provides truncated HCV E2 polypepides. The invention HCV E2 polypeptides lack the HVR1 region that provides immune protection against HCV. The present invention also provides immunogenic compositions of such polypeptides and the methods of use thereof.