alpha-Substituted beta-aminoethyl phosphonates

The present invention relates to novel alpha-substituted-beta-aminoethylphosphonate and alpha-substituted-beta-aminovinylphosphonate derivatives and their uses for lowering plasma levels of apo (a), Lp(a), apo B, apo B associated lipoproteins (low density lipoproteins and very low density lipoprotei...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: IFE, ROBERT, JOHN, AZOULAY, RAYMOND, ESCHENHOF, HARALD, DIEP, VINH, VAN, NGUYEN, LAN, MONG, PHAN, HIEU, TRUNG, NIESOR, ERIC, JOSEPH, BENTZEN, CRAIG, LEIGH
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to novel alpha-substituted-beta-aminoethylphosphonate and alpha-substituted-beta-aminovinylphosphonate derivatives and their uses for lowering plasma levels of apo (a), Lp(a), apo B, apo B associated lipoproteins (low density lipoproteins and very low density lipoproteins) and for lowering plasma levels of total cholesterol.