Method for detecting cells with numerical chromosomal abnormalities

The invention provides methods for detecting mitotic cells having numerical chromosomal abnormalities and agents inducing numericalchromosomal abnormalities in cells. In a preferred embodiment, the method comprises staining a cell with a mitotic marker: that detects cells in mitosis, and a quantitat...

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Hauptverfasser: MUEHLBAUER, PAULA A, SCHULER, MAIK J
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention provides methods for detecting mitotic cells having numerical chromosomal abnormalities and agents inducing numericalchromosomal abnormalities in cells. In a preferred embodiment, the method comprises staining a cell with a mitotic marker: that detects cells in mitosis, and a quantitative DNA stain, indicating the amount of DNA in the mitotic cell. Stained cells are preferably analyzed by flow cytometry.