5-HYDROXYTRYPTAMINE RECEPTOR GENE POLYMORPHISMS AND RESPONSE TO TREATMENT

Correlations between polymorphisms in the 5-hydroxytryptamine 3 receptor gene, and/or polymorphisms in the UGT1A4 gene, and a subject's phenotypic response to treatment with 5-hydroxytryptamine ligands are described. Methods of screening subjects to aid in treatment, methods of screening 5HT li...

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Hauptverfasser: HUGHES, ARLENE, R, MANASCO, PENELOPE, K, DAVIS, KOURTNEY, J, FLING, MARY, E, STUBBINS, MICHAEL, J
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Correlations between polymorphisms in the 5-hydroxytryptamine 3 receptor gene, and/or polymorphisms in the UGT1A4 gene, and a subject's phenotypic response to treatment with 5-hydroxytryptamine ligands are described. Methods of screening subjects to aid in treatment, methods of screening 5HT ligands, and methods of treatment are presented.