Process for the preparation of 2-(4-Alkyl-1-Piperazinyl)-Benzaldehyde and -Benzylidenyl compounds by Nucleophilc Aromatic Substitution of 2-Fluorobenzaldehyde with 4-Alkyl-1-Piperazine in Water as Solvent

Process for the preparation of 2-(4-Alkyl-1-Piperazinyl)-Benzaldehyde and -Benzylidenyl compounds by Nucleophilc Aromatic Substitution of 2-Fluorobenzaldehyde with 4-Alkyl-1-Piperazine in Water as Solvent

A process for the preparation of a compound of formula I: wherein R is (C1-C6) alkyl; comprising the step of allowing a compound of formula III: to react with a compound of formula IV: in the presence of a metal carbonate, characterized by the use of water as solvent. Further, a process for the prep...

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Bibliographische Detailangaben
Hauptverfasser: WALINSKY, STANLEY WALTER, SINAY JR., TERRY GENE, RAINVILLE, JOSEPH PHILIP
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:A process for the preparation of a compound of formula I: wherein R is (C1-C6) alkyl; comprising the step of allowing a compound of formula III: to react with a compound of formula IV: in the presence of a metal carbonate, characterized by the use of water as solvent. Further, a process for the preparation of a compound of formula II: involving the above mentioned process.d