NOVEL DUAL OXIDASES AS MITOGENIC AND ENDOCRINE REGULATORS

The present invention relates to new genes encoding for the production of novel proteins involved in generation of reactive oxygen intermediates and in peroxidative reactions that affect biological functions including cell division, thyroid hormone biosynthesis and tissue fibrosis. The present inven...

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Bibliographische Detailangaben
Hauptverfasser:	SHARLING, LISA, GRIENDLING, KATHY, K, EDENS, WILLIAM, A, LAMBETH, J., DAVID, ARNOLD, REBECCA, S, BENIAN, GUY, CHENG, GUANGIJIE, LASSEGUE, BERNARD, P
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to new genes encoding for the production of novel proteins involved in generation of reactive oxygen intermediates and in peroxidative reactions that affect biological functions including cell division, thyroid hormone biosynthesis and tissue fibrosis. The present invention also provides vectors containing these genes, cells transfected with these vectors, antibodies raised against these novel proteins, kits for detection, localization and measurement of these genes and proteins, and methods to determine the activity of drugs to affect the activity of the proteins of the present invention.