PEROXIDE-BASED ANTIMALARIAL COMPOUNDS

PEROXIDE-BASED ANTIMALARIAL COMPOUNDS

A compound of formula (I) wherein R is selected from H, Me, CF3, OMe, F or naphthyl; or a compound of formula (II) wherein R is selected from H, Me, CF3, OMe, F, naphthyl or t-Bu. These compounds are useful in the treatment of malaria and also in the treatment of cancers and proliferative disorders.

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Bibliographische Detailangaben
Hauptverfasser: WARD, STEPHEN ANDREW, O'NEILL, PAUL MICHAEL
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:A compound of formula (I) wherein R is selected from H, Me, CF3, OMe, F or naphthyl; or a compound of formula (II) wherein R is selected from H, Me, CF3, OMe, F, naphthyl or t-Bu. These compounds are useful in the treatment of malaria and also in the treatment of cancers and proliferative disorders.