PYRIMIDINE-4-ONE DERIVATIVE AS LDL-PLA2 INHIBITOR

Pyrimidinone compounds of formula (I) are inhibitors of the enzyme LpPLA2 and are useful in the treatment of atherosclerosis

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Bibliographische Detailangaben
Hauptverfasser:	IFE, ROBERT, JOHN, PINTO, IVAN, LEO, STANWAY, STEVEN, JAMES, SMITH, STEPHEN, ALLAN, LEACH, COLIN, ANDREW, HICKEY, DEIRDRE, MARY, B
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Pyrimidinone compounds of formula (I) are inhibitors of the enzyme LpPLA2 and are useful in the treatment of atherosclerosis