COMPOUNDS HAVING ANTITUMOR ACTIVITY: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

The present invention relates to novel derivatives of Andrographolide, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, and their pharmaceutically acceptable solvates. The novel derivatives of Andrographolide have the general formula (I)The andrographolide derivatives...

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Hauptverfasser: POTHUKUCHI, SAIRAM, PILLAI, SUNILKUMAR BHADRAMMA KOCHUNARAYANA, RAJAGOPAL, SRIRAM, CHAKRABARTI, RANJAN, NANDURI, SRINIVAS
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to novel derivatives of Andrographolide, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, and their pharmaceutically acceptable solvates. The novel derivatives of Andrographolide have the general formula (I)The andrographolide derivatives represented by general formula (I) are useful for treating cancer, HSV, HIV, psoriasis, restonosis, atherosclerosis, other cardiovascular disorders, and can be used as antiviral, antimalarial, antibacterial, hepatoprotective, and immunomodulating agents and for treatment of other metabolic disorders.