SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS

This invention is directed to oxoazaheterocyclyl compounds which inhibit Factor Xa, to oxoazaheterocyclyl compounds which inhibit both Factor Xa and Factor IIa, to pharmaceutical compositions comprising these compounds, to intermediates useful for preparing these compounds, to a method of directly i...

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Bibliographische Detailangaben
Hauptverfasser:	LAU, WAN, F, PAULS, HEINZ, W, LI, AIWEN, POLI, GREGORY, B, MYERS, MICHAEL, R, CONDON, STEPHEN, M, BURNS, CHRISTOPHER J, HANNEY, BARBARA, A, JIANG, JOHN, Z, EWING, WILLIAM, R, HE, WEI, DAVIS, RODERICK, S, BECKER, MICHAEL, R, SPADA, ALFRED, P, CHOI-SLEDESKI, YONG, MI
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention is directed to oxoazaheterocyclyl compounds which inhibit Factor Xa, to oxoazaheterocyclyl compounds which inhibit both Factor Xa and Factor IIa, to pharmaceutical compositions comprising these compounds, to intermediates useful for preparing these compounds, to a method of directly inhibiting Factor Xa and to a method of simultaneously directly inhibiting Factor Xa and Factor IIa.