PROCESSES FOR THE PREPARATION OF (R)-G(A)-(2,3-DIMETHOXYPHENYL)-1-(2-(4-FLUOROPHENYL)ETHYL)-4-PIPERIDINEMETHANOL

The present invention provides various processes for the preparation of (R)-±-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol. These processes may be characterized by the following scheme:

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Bibliographische Detailangaben
Hauptverfasser: HAWTORNE ROBERT A, MINISH, SHARON K, SKULTETY PAUL F, DAUGS, EDWARD D, BINA ALAN G, ORTYL THOMAS T, HITT JAMES E, FLEMMING HANS-WOLFRAM, RAJEWSKI LIAN G, SACK MARVIN J, HILPERT THOMAS H.E, STOLTZ-DUNN SANDRA K, EVANS JONATHAN C, GUILLAMOT GERARD, KING CHI-HSIN R, TIGNER ALONZO L, KOEK JOHANNES N, MARGOLIN ALEXEY L, LASKOVICS FREDERICK M, LEFLER JOHN M
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention provides various processes for the preparation of (R)-±-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol. These processes may be characterized by the following scheme: