GENERATION OF THERAPEUTIC MICROFOAM

A microfoam for use in sclerotherapy, comprises a physiologically acceptable blood dispersible gas capable of being substantially completely dissolved in or absorbed by blood, wherein the physiologically acceptable blood dispersible gas includes less than 40% v/v nitrogen and comprises at least 50%...

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Bibliographische Detailangaben
Hauptverfasser: BOORMAN, TIMOTHY, DAVID, OSMAN, TARIQ, WRIGHT, DAVID, DAKIN, IORWERTH, FLYNN, SHEILA, BRONWEN, HARMAN, ANTHONY, DAVID
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:A microfoam for use in sclerotherapy, comprises a physiologically acceptable blood dispersible gas capable of being substantially completely dissolved in or absorbed by blood, wherein the physiologically acceptable blood dispersible gas includes less than 40% v/v nitrogen and comprises at least 50% oxygen or carbon dioxide; and an aqueous sclerosant liquid suitable for use in sclerotherapy, said aqueous sclerosant liquid being aqueous polidocanol or sodium tetradecyl sulphate; wherein the microfoam has a density of from 0.07 to 0.19 g/cm 3 and is capable of being passed down a 21 gauge needle such that 50% or more by number of its gas bubbles of at least 25 µm are of 150 µm diameter or less and at least 95% of these bubbles are of 280 µm diameter or less.