BENZYLMALTOTRIOSIDES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION

This invention provides smooth muscle cell proliferation inhibitors of formula (I) having the structure wherein X is (A) wherein R , R , R , R , R , R , R , R , R and R , are each, independently, hydrogen, acyl of 2-7 carbon atoms, perfluoroacyl of 2-10 carbon atoms, alkyl of 1-6 carbon atoms, perfl...

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Bibliographische Detailangaben
1. Verfasser: DOLLINGS, PAUL, JEFFREY
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:This invention provides smooth muscle cell proliferation inhibitors of formula (I) having the structure wherein X is (A) wherein R , R , R , R , R , R , R , R , R and R , are each, independently, hydrogen, acyl of 2-7 carbon atoms, perfluoroacyl of 2-10 carbon atoms, alkyl of 1-6 carbon atoms, perfluoroalkyl of 1-6 carbon atoms, benzoyl, benzyl or -SO3M; M is hydrogen, lithium, sodium, potassium or ammonium; R is hydrogen, alkyl of 1-6 carbon atoms, perfluoroalkyl of 1-6 carbon atomes, halogen, nitrile, nitro, or alkoxy of 1-6 carbon atoms; R is hydrogen, nitro, amino, acylamino of 2-7 carbon atoms, perfluoroacylamino of 2-7 carbon atoms, alkylamino of 1-6 carbon atoms, perfluoroalkylamino of 1-6 carbon atoms, dialklylamino where each alkyl chain is independently 1-6 carbon atoms, perfluorodialklylamino where each alkyl chain is independently 1-6 carbon atoms, alkylsulfonylamino of 1-6 carbon atoms, perfluoroalkyl-sulfonylamino of 1-6 carbon atoms, arylsulfonylamino of 6-10 carbon atoms or arylsulfonylamino substituted with halo of 6-10 carbon atoms; or a pharmaceutically acceptable salt thereof.