Non-squamous epithelium-specific transcription

The invention relates to the field of cancer therapy and diagnosis, in particular of carcinomas. The invention provides an isolated and/or recombinant nucleic acid comprising a tissue specific promotor or functional fragment thereof allowing for expression of a nucleic acid of interest operably link...

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Bibliographische Detailangaben
Hauptverfasser: DE LEIJ, LOU FRANCISCUS MARIA HUBERTUS, VAN DER MOLEN, HENK, TERPSTRA, PETER, HARMSEN, MARTIN CONRAD, RUITERS, MARCEL HERMAN JOSEF, MCLAUGHLIN, PAMELA MARIJKE JANE, DOKTER, WILLEM HENDRIK ABRAHAM
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention relates to the field of cancer therapy and diagnosis, in particular of carcinomas. The invention provides an isolated and/or recombinant nucleic acid comprising a tissue specific promotor or functional fragment thereof allowing for expression of a nucleic acid of interest operably linked to said promotor or functional fragment thereof in a cancer cell wherein said expression in said cancer cell is essentially carcinoma selective.