COMBINED VACCINE AGAINST BOTH HAV AND MEASLE VIRUS AND METHOD OF PRODUCING IT

A combined hepatitis A-measles live vaccine, its lyophilized formulations with enhanced storage stability and methods of preparing the same by mixing the viral stocks of hepatitis A virus and measles virus or by propagating the two viruses on same diploid cell substrate are disclosed. The combined l...

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Hauptverfasser: LIU, LISHA, LIU, JINGYE, LI, GUANGPU, WANG, WEI, HUANG, JINFENG, WANG, PENGFU, XIE, BAOSHENG, SONG, ZONGMING, WANG, MEIHUA, QU, CUIBO, NAN, YIFAN, GUO, JIANJUN, WAN, ZONGJU
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:A combined hepatitis A-measles live vaccine, its lyophilized formulations with enhanced storage stability and methods of preparing the same by mixing the viral stocks of hepatitis A virus and measles virus or by propagating the two viruses on same diploid cell substrate are disclosed. The combined live vaccine thus prepared is a useful vaccine for preventing the infections with hepatitis A and measles without causing any interference between antigenicity of the two viruses and any serious adverse events due to their mixing or co-culturing.