Substituted thiazoles for the treatment of inflammation

A class of substituted thiazolyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula II wherein R is selected from methyl and amino; wherein R is selected from optionally substituted aryl, cycloalkyl, cyc...

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Bibliographische Detailangaben
Hauptverfasser:	ROGERS, KATHY L, COLLINS, PAUL W, TALLEY, JOHN J, ROGIER, DONALD J., JR, KRAMER, STEVEN W, ROGERS, ROLAND S, PENNING, THOMAS D, CARTER, JEFFREY S
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A class of substituted thiazolyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula II wherein R is selected from methyl and amino; wherein R is selected from optionally substituted aryl, cycloalkyl, cycloalkenyl and heterocyclic; and wherein R is selected from hydrogen or specified substituents; or a pharmaceutically-acceptable salt thereof.