MULTIVALENT AVB3 AND METASTASIS-ASSOCIATED RECEPTOR LIGANDS

The present invention relates to pharmaceutical compounds which are multivalent avb3 receptor/metastasis-associated receptor ligands. The use of these multivalent ligands alone or in conjunction with other agents in pharmaceutical compositions, and in methods for treating conditions mediated by avb3...

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Hauptverfasser: FOK, KAM, F, TJOENG, FOE, S
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to pharmaceutical compounds which are multivalent avb3 receptor/metastasis-associated receptor ligands. The use of these multivalent ligands alone or in conjunction with other agents in pharmaceutical compositions, and in methods for treating conditions mediated by avb3 for the treatment of cancer and other angiogenic diseases, such as diabetic retinopathy, arthritis, hemangiomas, and psoriasis, are also disclosed.