NOVEL HETEROCYCLIC COMPOUNDS

The present invention relates to novel N-substituted azaheterocyclic compounds of general formula (I) wherein X, Z, R , R and r are as defined in the detailed part of the present description, or salts thereof, to methods for their preparation, to compositions containing them, and to their use for th...

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Hauptverfasser: JORGENSEN, TINE, KROGH, SINDELAR, KAREL, HOHLWEG, ROLF, OLSEN, UFFE, BANG, ANDERSEN, KNUD, ERIK, POLIVKA, ZDENEK
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creator JORGENSEN, TINE, KROGH
SINDELAR, KAREL
HOHLWEG, ROLF
OLSEN, UFFE, BANG
ANDERSEN, KNUD, ERIK
POLIVKA, ZDENEK
description The present invention relates to novel N-substituted azaheterocyclic compounds of general formula (I) wherein X, Z, R , R and r are as defined in the detailed part of the present description, or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation, as well as their use for treatment of indications caused by or related to the secretion and circulation of insulin antagonising peptides, e.g. non-insulin-dependent diabetes mellitus (NIDDM) and ageing-associated obesity.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title NOVEL HETEROCYCLIC COMPOUNDS
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