NOVEL HETEROCYCLIC COMPOUNDS

The present invention relates to novel N-substituted azaheterocyclic compounds of general formula (I) wherein X, Z, R , R and r are as defined in the detailed part of the present description, or salts thereof, to methods for their preparation, to compositions containing them, and to their use for th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	JORGENSEN, TINE, KROGH, SINDELAR, KAREL, HOHLWEG, ROLF, OLSEN, UFFE, BANG, ANDERSEN, KNUD, ERIK, POLIVKA, ZDENEK
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to novel N-substituted azaheterocyclic compounds of general formula (I) wherein X, Z, R , R and r are as defined in the detailed part of the present description, or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation, as well as their use for treatment of indications caused by or related to the secretion and circulation of insulin antagonising peptides, e.g. non-insulin-dependent diabetes mellitus (NIDDM) and ageing-associated obesity.