INTERLEUKIN-6 PRODUCTION INHIBITORS

An interleukin-6 production inhibitor is provided containing a methanebisphosphonic acid derivative as an active component, which has inhibitory effects on interleukin-6 production and is useful in prevention and treatment of diseases due to abnormal production of the interleukin-6. This pharmaceuti...

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Bibliographische Detailangaben
Hauptverfasser: KOIKE, JUNZO, OKAZAKI, SEIJI, FUNABA, YURIKO, TANAHASHI, MASAHIKO, ITO, MASATOSHI
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:An interleukin-6 production inhibitor is provided containing a methanebisphosphonic acid derivative as an active component, which has inhibitory effects on interleukin-6 production and is useful in prevention and treatment of diseases due to abnormal production of the interleukin-6. This pharmaceutical is anticipated to have effects in prevention and treatment of diseases related to the interleukin-6, for example, thrombocytosis, inflammatory diseases, abnormal immune response diseases, osteoporosis, rheumatoid arthritis, hypercalcemia, multiple myeloma, cachexia, and nephritis.