THREE-DIMENSIONAL STRUCTURES AND MODELS OF Fc RECEPTORS AND USES THEREOF

Disclosed are crystals, crystal structure FcgammaRIIa protein, three dimensional coordinates of FcgammaRIIa protein, and structures and models derived from the FcgammaRIIa structure. Also disclosed are crystals of FcepsilonRI protein and three dimensional coordinates of FcepsilonRI protein monomers...

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Bibliographische Detailangaben
Hauptverfasser:	MAXWELL, KELLY, F, MATTHEWS, BARRY, R, BAELL, JONATHAN, B, HOGARTH, P., MARK, POWELL, MAREE, S, MCKENZIE, IAN, F., C, GARRETT, THOMAS, P., J, MCCARTHY, THOMAS, D, PIETERSZ, GEOFFREY, A, EPA, VIDANA
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	APPARATUS THEREFOR BEER BIOCHEMISTRY CALCULATING CHEMISTRY COMPOSITIONS THEREOF COMPUTING COUNTING CULTURE MEDIA ELECTRIC DIGITAL DATA PROCESSING ENZYMOLOGY GENERAL METHODS OF ORGANIC CHEMISTRY HUMAN NECESSITIES HYGIENE IMAGE DATA PROCESSING OR GENERATION, IN GENERAL MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Disclosed are crystals, crystal structure FcgammaRIIa protein, three dimensional coordinates of FcgammaRIIa protein, and structures and models derived from the FcgammaRIIa structure. Also disclosed are crystals of FcepsilonRI protein and three dimensional coordinates of FcepsilonRI protein monomers and dimers derived from the FcgammaRIIa structure. Also disclosed are three dimensional coordinates of FcgammaRIIIb proteins and models of FcgammaRIIIb derived from the FcgammaRIIa structure. The present invention also includes methods to produce such crystals, crystal structures and models. Uses of such crystals, crystal structures and models are also disclosed, including structure based drug design and therapeutic compositions.