SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS

This invention is directed to oxoazaheterocycyl compounds which inhibit Factor Xa, to oxoazaheterocycyl compounds which inhibit both Factor Xa and Factor IIa, to pharmaceutical compositions comprising these compounds, to intermediates useful for preparing these compounds, to a method of directly inh...

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Hauptverfasser: LAU, WAN, F, PAULS, HEINZ, W, LI, AIWEN, POLI, GREGORY, B, MYERS, MICHAEL, R, CONDON, STEPHEN, M, HANNEY, BARBARA, A, JIANG, JOHN, Z, EWING, WILLIAM, R, HE, WEI, DAVIS, RODERICK, S, BECKER, MICHAEL, R, SPADA, ALFRED, P, CHOI-SLEDESKI, YONG, MI, BURNS, CHRISTOPHER, J
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creator LAU, WAN, F
PAULS, HEINZ, W
LI, AIWEN
POLI, GREGORY, B
MYERS, MICHAEL, R
CONDON, STEPHEN, M
HANNEY, BARBARA, A
JIANG, JOHN, Z
EWING, WILLIAM, R
HE, WEI
DAVIS, RODERICK, S
BECKER, MICHAEL, R
SPADA, ALFRED, P
CHOI-SLEDESKI, YONG, MI
BURNS, CHRISTOPHER, J
description This invention is directed to oxoazaheterocycyl compounds which inhibit Factor Xa, to oxoazaheterocycyl compounds which inhibit both Factor Xa and Factor IIa, to pharmaceutical compositions comprising these compounds, to intermediates useful for preparing these compounds, to a method of directly inhibiting Factor Xa and to a method of simultaneously directly inhibiting Factor Xa and Factor IIa.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS
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