SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS

This invention is directed to oxoazaheterocycyl compounds which inhibit Factor Xa, to oxoazaheterocycyl compounds which inhibit both Factor Xa and Factor IIa, to pharmaceutical compositions comprising these compounds, to intermediates useful for preparing these compounds, to a method of directly inh...

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Bibliographische Detailangaben
Hauptverfasser:	LAU, WAN, F, PAULS, HEINZ, W, LI, AIWEN, POLI, GREGORY, B, MYERS, MICHAEL, R, CONDON, STEPHEN, M, HANNEY, BARBARA, A, JIANG, JOHN, Z, EWING, WILLIAM, R, HE, WEI, DAVIS, RODERICK, S, BECKER, MICHAEL, R, SPADA, ALFRED, P, CHOI-SLEDESKI, YONG, MI, BURNS, CHRISTOPHER, J
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention is directed to oxoazaheterocycyl compounds which inhibit Factor Xa, to oxoazaheterocycyl compounds which inhibit both Factor Xa and Factor IIa, to pharmaceutical compositions comprising these compounds, to intermediates useful for preparing these compounds, to a method of directly inhibiting Factor Xa and to a method of simultaneously directly inhibiting Factor Xa and Factor IIa.