Process for the preparation of 2-chloro-5-chloromethyl-thiazole

Process for the preparation of 2-chloro-5-chloromethyl-thiazole

Preparation of 2-chloro-5-chloromethyl-thiazole (I) by reacting 2-(bromo or chloro)-allylisothiocyanate (II) with a chlorinating agent is carried out in presence of a dipolar, aprotic solvent. Preparation of 2-chloro-5-chloromethyl-thiazole of formula (I) involves reacting 2-haloallyl isothiocyanate...

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Bibliographische Detailangaben
1. Verfasser: DECKER, MATTHIAS
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Preparation of 2-chloro-5-chloromethyl-thiazole (I) by reacting 2-(bromo or chloro)-allylisothiocyanate (II) with a chlorinating agent is carried out in presence of a dipolar, aprotic solvent. Preparation of 2-chloro-5-chloromethyl-thiazole of formula (I) involves reacting 2-haloallyl isothiocyanate of formula (II) with a chlorinating agent in presence of a dipolar, aprotic solvent. X = Cl or Br.