COMPOSITIONS AND METHODS FOR SYSTEMIC DELIVERY OF ORAL VACCINES AND THERAPEUTIC AGENTS

Compositions and methods of oral delivery of an antigen or therapeutic agent to the general circulation using a modified botulinum toxin which is capable of translocating from the gut to the general circulation but which is altered to be nontoxic are provided.

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Bibliographische Detailangaben
Hauptverfasser: MAKSYMOWYCH, ANDREW, KIYATKIN, NIKITA, SIMPSON, LANCE
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Compositions and methods of oral delivery of an antigen or therapeutic agent to the general circulation using a modified botulinum toxin which is capable of translocating from the gut to the general circulation but which is altered to be nontoxic are provided.