Pyranoquinoline derivatives as inhibitors of cell proliferation
Pharmaceutical compounds of the formula R is phenyl or heteroaryl selected from thienyl, pyridyl, benzothienyl, quinolinyl, benzofuranyl or benzimidazolyl, said phenyl and heteroaryl groups being optionally substituted, or R is furanyl optionally substituted with C1-4 alkyl; R is nitrile, carboxy, -...
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Sprache: | eng ; fre ; ger |
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Zusammenfassung: | Pharmaceutical compounds of the formula R is phenyl or heteroaryl selected from thienyl, pyridyl, benzothienyl, quinolinyl, benzofuranyl or benzimidazolyl, said phenyl and heteroaryl groups being optionally substituted, or R is furanyl optionally substituted with C1-4 alkyl; R is nitrile, carboxy, -COOR where R is an ester group, -CONR R where R and R are each hydrogen or C1-4 alkyl, or R SO2- where R is C1-4 alkyl or optionally substituted phenyl; R is -NR R , -NHCOR , -N(COR )2, -N=CHOR where R and R are each hydrogen or C1-4 alkyl, or -NHSO2R where R is C1-4 alkyl or optionally substituted phenyl; or where X is C2-4 alkylene; and the group represents a pyridine ring fused to the benzopyran nucleus; and salts thereof. |
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