4- (THIEN-3-YL)METHYL] IMIDAZOLE DERIVATIVES HAVING ALPHA2-ADRENOCEPTOR AGONISTIC ACTIVITY

4- (THIEN-3-YL)METHYL] IMIDAZOLE DERIVATIVES HAVING ALPHA2-ADRENOCEPTOR AGONISTIC ACTIVITY

Described herein are 4-[(thien-3-yl)methyl]-imidazoles of the formula: wherein R is hydrogen or methyl, and X is C1-4alkyl, bromine or chlorine; or wherein Y is hydrogen, C1-4alkyl, bromine or chlorine, and Z is C1-44alkyl, bromine or chlorine which have exceptional analgesic activity.

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Bibliographische Detailangaben
Hauptverfasser: BOYD, ROBERT, E, PRESS, JEFFREY, B, RASMUSSEN, CHRIS, ROYCE
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Described herein are 4-[(thien-3-yl)methyl]-imidazoles of the formula: wherein R is hydrogen or methyl, and X is C1-4alkyl, bromine or chlorine; or wherein Y is hydrogen, C1-4alkyl, bromine or chlorine, and Z is C1-44alkyl, bromine or chlorine which have exceptional analgesic activity.