Live attenuated salmonella vaccine

Live attenuated salmonella vaccine

The present invention is related to a vaccine for inducing an immune response to a Salmonella strain in an animal, including a human, characterised in that it comprises a pharmaceutically acceptable carrier and a genetically modified Salmonella strain which is in an amount effective to produce an im...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GUBBELS, ELINA FRIEDA IRENA ALBERT, DE GREVE, HENRI MARCEL JOZEF, HERNALSTEENS, JEAN-PIERRE ERNEST CLEMENT
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention is related to a vaccine for inducing an immune response to a Salmonella strain in an animal, including a human, characterised in that it comprises a pharmaceutically acceptable carrier and a genetically modified Salmonella strain which is in an amount effective to produce an immune response in said animal, including human, and comprises a modification in its wild type DNA sequence SEQ ID NO 01, any of the DNA sequences from the same operon as SEQ ID NO 01 and/or any regulatory sequence of any of the said DNA sequences.