LIPOSOME ENCAPSULATED AMPHIPHILIC DRUG COMPOSITIONS

LIPOSOME ENCAPSULATED AMPHIPHILIC DRUG COMPOSITIONS

PCT No. PCT/EP97/01384 Sec. 371 Date Nov. 19, 1998 Sec. 102(e) Date Nov. 19, 1998 PCT Filed Mar. 19, 1997 PCT Pub. No. WO97/34582 PCT Pub. Date Sep. 25, 1997A process for the entrapment of amphiphilic compounds as uncharged or ionic with different mole ratios of phospholipid to the amphiphilic compo...

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Bibliographische Detailangaben
Hauptverfasser: BRASSEUR, ROBERT, LEGROS, FRANZ, ALAFANDY, MOKARRAM, CAMU, FREDERIC, BOUFFIOUX, OLIVIER
Format: Patent
Sprache:eng ; fre ; ger
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:PCT No. PCT/EP97/01384 Sec. 371 Date Nov. 19, 1998 Sec. 102(e) Date Nov. 19, 1998 PCT Filed Mar. 19, 1997 PCT Pub. No. WO97/34582 PCT Pub. Date Sep. 25, 1997A process for the entrapment of amphiphilic compounds as uncharged or ionic with different mole ratios of phospholipid to the amphiphilic compound. Preparations of ionic species of amphiphilic compounds in the absence of crystals can be prepared, while preparations of uncharged amphiphilic compounds can be prepared with the compound exclusively entrapped inside the liposomes, or partly entrapped inside the liposomes with extraliposomal crystals.