A method of preparing 16-dehydro vitamin D compounds
The invention relates to a new method of preparing 16-dehydro vitamin D compounds having formula I wherein: R has the epi-configuration or the normal configuration and represents straight or branched C1-6-alkyl, C2-6-alkenyl, C3-6-cycloalkyl, or an aromatic group optionally substituted with halogen,...
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre ; ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | FALL, Y ZORGDRAGER, J MOURINO, A V.D. VELDE, J.P FERNANDEZ-GACIO, A HALKES, K.M HALKES, S.J DEL LOS ANGELES REY, M |
| description | The invention relates to a new method of preparing 16-dehydro vitamin D compounds having formula I wherein: R has the epi-configuration or the normal configuration and represents straight or branched C1-6-alkyl, C2-6-alkenyl, C3-6-cycloalkyl, or an aromatic group optionally substituted with halogen, C1-3-alkyl or alkoxy, Z is a saturated or unsaturated straight hydrocarbon group or oxahydrocarbon group containing 3-6 C-atoms which may be substituted with OH, F, alkyl (C1-3) or cycloalkyl (C3-5), R1 is hydrogen or an hydroxy protecting group, R2 is hydrogen or hydroxy, and A and B represent hydrogen or methyl, or together form the methylene group, to the new compounds having this formula and to new intermediates obtainable according to this process. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP0884308B1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP0884308B1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP0884308B13</originalsourceid><addsrcrecordid>eNrjZDBxVMhNLcnIT1HIT1MoKEotSCzKzEtXMDTTTUnNqEwpylcoyyxJzM3MU3BRSM7PLcgvzUsp5mFgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8a4BBhYWJsYGFk6GxkQoAQBzCCuZ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>A method of preparing 16-dehydro vitamin D compounds</title><source>esp@cenet</source><creator>FALL, Y ; ZORGDRAGER, J ; MOURINO, A ; V.D. VELDE, J.P ; FERNANDEZ-GACIO, A ; HALKES, K.M ; HALKES, S.J ; DEL LOS ANGELES REY, M</creator><creatorcontrib>FALL, Y ; ZORGDRAGER, J ; MOURINO, A ; V.D. VELDE, J.P ; FERNANDEZ-GACIO, A ; HALKES, K.M ; HALKES, S.J ; DEL LOS ANGELES REY, M</creatorcontrib><description>The invention relates to a new method of preparing 16-dehydro vitamin D compounds having formula I wherein: R has the epi-configuration or the normal configuration and represents straight or branched C1-6-alkyl, C2-6-alkenyl, C3-6-cycloalkyl, or an aromatic group optionally substituted with halogen, C1-3-alkyl or alkoxy, Z is a saturated or unsaturated straight hydrocarbon group or oxahydrocarbon group containing 3-6 C-atoms which may be substituted with OH, F, alkyl (C1-3) or cycloalkyl (C3-5), R1 is hydrogen or an hydroxy protecting group, R2 is hydrogen or hydroxy, and A and B represent hydrogen or methyl, or together form the methylene group, to the new compounds having this formula and to new intermediates obtainable according to this process.</description><edition>7</edition><language>eng ; fre ; ger</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2003</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20030416&DB=EPODOC&CC=EP&NR=0884308B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20030416&DB=EPODOC&CC=EP&NR=0884308B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FALL, Y</creatorcontrib><creatorcontrib>ZORGDRAGER, J</creatorcontrib><creatorcontrib>MOURINO, A</creatorcontrib><creatorcontrib>V.D. VELDE, J.P</creatorcontrib><creatorcontrib>FERNANDEZ-GACIO, A</creatorcontrib><creatorcontrib>HALKES, K.M</creatorcontrib><creatorcontrib>HALKES, S.J</creatorcontrib><creatorcontrib>DEL LOS ANGELES REY, M</creatorcontrib><title>A method of preparing 16-dehydro vitamin D compounds</title><description>The invention relates to a new method of preparing 16-dehydro vitamin D compounds having formula I wherein: R has the epi-configuration or the normal configuration and represents straight or branched C1-6-alkyl, C2-6-alkenyl, C3-6-cycloalkyl, or an aromatic group optionally substituted with halogen, C1-3-alkyl or alkoxy, Z is a saturated or unsaturated straight hydrocarbon group or oxahydrocarbon group containing 3-6 C-atoms which may be substituted with OH, F, alkyl (C1-3) or cycloalkyl (C3-5), R1 is hydrogen or an hydroxy protecting group, R2 is hydrogen or hydroxy, and A and B represent hydrogen or methyl, or together form the methylene group, to the new compounds having this formula and to new intermediates obtainable according to this process.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2003</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDBxVMhNLcnIT1HIT1MoKEotSCzKzEtXMDTTTUnNqEwpylcoyyxJzM3MU3BRSM7PLcgvzUsp5mFgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8a4BBhYWJsYGFk6GxkQoAQBzCCuZ</recordid><startdate>20030416</startdate><enddate>20030416</enddate><creator>FALL, Y</creator><creator>ZORGDRAGER, J</creator><creator>MOURINO, A</creator><creator>V.D. VELDE, J.P</creator><creator>FERNANDEZ-GACIO, A</creator><creator>HALKES, K.M</creator><creator>HALKES, S.J</creator><creator>DEL LOS ANGELES REY, M</creator><scope>EVB</scope></search><sort><creationdate>20030416</creationdate><title>A method of preparing 16-dehydro vitamin D compounds</title><author>FALL, Y ; ZORGDRAGER, J ; MOURINO, A ; V.D. VELDE, J.P ; FERNANDEZ-GACIO, A ; HALKES, K.M ; HALKES, S.J ; DEL LOS ANGELES REY, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP0884308B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2003</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>FALL, Y</creatorcontrib><creatorcontrib>ZORGDRAGER, J</creatorcontrib><creatorcontrib>MOURINO, A</creatorcontrib><creatorcontrib>V.D. VELDE, J.P</creatorcontrib><creatorcontrib>FERNANDEZ-GACIO, A</creatorcontrib><creatorcontrib>HALKES, K.M</creatorcontrib><creatorcontrib>HALKES, S.J</creatorcontrib><creatorcontrib>DEL LOS ANGELES REY, M</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>FALL, Y</au><au>ZORGDRAGER, J</au><au>MOURINO, A</au><au>V.D. VELDE, J.P</au><au>FERNANDEZ-GACIO, A</au><au>HALKES, K.M</au><au>HALKES, S.J</au><au>DEL LOS ANGELES REY, M</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>A method of preparing 16-dehydro vitamin D compounds</title><date>2003-04-16</date><risdate>2003</risdate><abstract>The invention relates to a new method of preparing 16-dehydro vitamin D compounds having formula I wherein: R has the epi-configuration or the normal configuration and represents straight or branched C1-6-alkyl, C2-6-alkenyl, C3-6-cycloalkyl, or an aromatic group optionally substituted with halogen, C1-3-alkyl or alkoxy, Z is a saturated or unsaturated straight hydrocarbon group or oxahydrocarbon group containing 3-6 C-atoms which may be substituted with OH, F, alkyl (C1-3) or cycloalkyl (C3-5), R1 is hydrogen or an hydroxy protecting group, R2 is hydrogen or hydroxy, and A and B represent hydrogen or methyl, or together form the methylene group, to the new compounds having this formula and to new intermediates obtainable according to this process.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre ; ger |
| recordid | cdi_epo_espacenet_EP0884308B1 |
| source | esp@cenet |
| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | A method of preparing 16-dehydro vitamin D compounds |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-09T17%3A20%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=FALL,%20Y&rft.date=2003-04-16&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP0884308B1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |