A method of purifying sodium hyaluronate

Highly purified sodium hyaluronate having a low content of pyrogen is obtained by adding a salt and a water-soluble organic solvent to a solution containing sodium hyaluronate, or to a sodium hyaluronate solution previously filtered through a positively charged filter, precipitating and sedimenting...

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Hauptverfasser: SUGA, SHIGENORI, MUROI, KENICHI, KINOSHITA, TADASHI, GOTO, JOJI
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Highly purified sodium hyaluronate having a low content of pyrogen is obtained by adding a salt and a water-soluble organic solvent to a solution containing sodium hyaluronate, or to a sodium hyaluronate solution previously filtered through a positively charged filter, precipitating and sedimenting the sodium hyaluronate and taking out a supernatant to remove pyrogen.