DETECTION OF HUMAN ALPHA-THALASSEMIA MUTATIONS AND THEIR USE AS PREDICTORS OF BLOOD-RELATED DISORDERS

The invention is based on the discovery that adults having a genotype comprising a hemoglobin alpha -gene deletion are significantly more likely to be hypertensive than adults having a normal ( alpha alpha / alpha alpha ) gentoype. The invention provides an improved method for determining a human su...

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Bibliographische Detailangaben
1. Verfasser:	BOWIE, LEMUEL J
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention is based on the discovery that adults having a genotype comprising a hemoglobin alpha -gene deletion are significantly more likely to be hypertensive than adults having a normal ( alpha alpha / alpha alpha ) gentoype. The invention provides an improved method for determining a human subject's genotype at the alpha -gene loci; a method of screening a human subject for an increased potential of developing hypertension and other blood-related disorders; and provides an apparatus/kit for screening a human subject for a risk of developing hypertension and other blood-related disorders.