PROCESS FOR PRODUCING 3-NORCEPHEM COMPOUNDS
The present invention provides a process for preparing 3-norcephem compound represented by the formula (2), characterized in that a hydride reagent is acted on a halogenated beta -lactam compound represented by the formula (1) in the presence of a cuprous compound wherein R1 is a hydrogen atom, amin...
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Format: | Patent |
Sprache: | eng ; fre ; ger |
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Zusammenfassung: | The present invention provides a process for preparing 3-norcephem compound represented by the formula (2), characterized in that a hydride reagent is acted on a halogenated beta -lactam compound represented by the formula (1) in the presence of a cuprous compound wherein R1 is a hydrogen atom, amino group or protected amino group, R2 is an aryl or substituted aryl, n is 0 to 2, R3 is a hydrogen atom or carboxylic acid protective group, X is a halogen atom, and Y is a halogen atom or a leaving group wherein R1 and R3 are as defined above.r |
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