Process for the preparation of pyrimidine derivatives

Process for the preparation of pyrimidine derivatives

The present invention provides a novel process for the manufacture of pyrimidines of general formula I wherein R , R , R each independently represent hydrogen, C1-7-alkyl, or C1-7-alkoxy, A signifies -CN, a carbanionic R -alkynyl residue, in which R is hydrogen or C1-7-alkyl, or a carbanionic residu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: GOEHRING, WOLFGANG
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention provides a novel process for the manufacture of pyrimidines of general formula I wherein R , R , R each independently represent hydrogen, C1-7-alkyl, or C1-7-alkoxy, A signifies -CN, a carbanionic R -alkynyl residue, in which R is hydrogen or C1-7-alkyl, or a carbanionic residue of the malonic acid derivative of formula III in which B and B' independently represent -CN, -COOR , or -C(O)R , wherein R is alkyl or aryl. r