PIPERIDINE DERIVATIVES

PIPERIDINE DERIVATIVES

Piperidine derivatives represented by general formula (I) or pharmaceutically acceptable acid addition salts thereof: wherein n represents an integer of 0 or 1; X represents CH2, O or CH-CH3; R represents hydrogen, halogen, lower alkyl, hydroxy, lower alkoxy, lower alkylthio, lower alkylsulfinyl, lo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BEPPU, KOICHI, OKAYAMA, AKIRA, TANOUE, YOSHIHIRO, SAKAMOTO, OSAMI
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Piperidine derivatives represented by general formula (I) or pharmaceutically acceptable acid addition salts thereof: wherein n represents an integer of 0 or 1; X represents CH2, O or CH-CH3; R represents hydrogen, halogen, lower alkyl, hydroxy, lower alkoxy, lower alkylthio, lower alkylsulfinyl, lower alkylsulfonyl, substituted aminosulfonyl or nitro; R1 and R2 may be the same or different and each represents hydrogen or lower alkyl, are disclosed. The piperidine derivatives have an antagonism on Substance P and is useful as a preventive or remedy for asthma, vomiting, etc.