BENZOTHIAZOLES AND BENZOXAZOLES, AS WELL AS DRUGS CONTAINING THEM, THEIR USE AND METHODS OF PREPARING THEM

BENZOTHIAZOLES AND BENZOXAZOLES, AS WELL AS DRUGS CONTAINING THEM, THEIR USE AND METHODS OF PREPARING THEM

PCT No. PCT/EP96/01827 Sec. 371 Date Oct. 28, 1997 Sec. 102(e) Date Oct. 28, 1997 PCT Filed May 2, 1996 PCT Pub. No. WO96/35681 PCT Pub. Date Nov. 14, 1996The invention relates to benzothiazoles and benzoxazoles of general formula wherein R1 to R3, X, Z and n are defined as in claim 1, the enantiome...

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Hauptverfasser: BUDZINSKI, RALPH-MICHAEL, HALLERMAYER, GERHARD, MAIER, ROLAND, EISELE, BERNHARD, THOMAS, LEO, MARK, MICHAEL, MUELLER, PETER, HURNAUS, RUDOLF
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
FODDER
FOODS OR FOODSTUFFS
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Zusammenfassung:PCT No. PCT/EP96/01827 Sec. 371 Date Oct. 28, 1997 Sec. 102(e) Date Oct. 28, 1997 PCT Filed May 2, 1996 PCT Pub. No. WO96/35681 PCT Pub. Date Nov. 14, 1996The invention relates to benzothiazoles and benzoxazoles of general formula wherein R1 to R3, X, Z and n are defined as in claim 1, the enantiomers, diastereomers and salts thereof, particularly the physiologically acceptable acid addition salts thereof which have valuable properties, particularly an inhibitory effect on cholesterol biosynthesis, pharmaceutical compositions containing these compounds, the use thereof and processes for preparing them.