IGF/IGFBP COMPLEX FOR PROMOTING BONE FORMATION AND FOR REGULATING BONE REMODELING

IGF and IGFBP are administered to stimulate new bone formation in subjects with bone loss due to bone marrow disorders, connective tissue disorders, drugs, pregnancy, lactation, chronic hypophosphatemia, hyperphosphatasia, insulin-dependent diabetes mellitus, anorexia nervosa, cadmium poisoning, juv...

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Hauptverfasser: ADAMS, STEVEN, W, BAGI, CEDO, MARTIN, BROMMAGE, ROBERT, ROSEN, DAVID, M
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:IGF and IGFBP are administered to stimulate new bone formation in subjects with bone loss due to bone marrow disorders, connective tissue disorders, drugs, pregnancy, lactation, chronic hypophosphatemia, hyperphosphatasia, insulin-dependent diabetes mellitus, anorexia nervosa, cadmium poisoning, juvenile osteoporosis, Paget's disease of bone, osteoarthritis and periodontal disease. IGF-I and IGFBP-3 are optionally combined with agents that inhibit bone resorption.